Work

Immune Activation While on Potent Antiretroviral Therapy Can Predict Subsequent CD4+ T-Cell Increases Through 15 Years of Treatment

Year: 2020

Type: article

Abstract: While persistent T-cell activation has been cross-sectionally associated with poor CD4+ T-cell restoration in HIV-infected individuals maintaining antiretroviral treatment (ART)–mediated viral suppression, it remains unclear whether CD8+ T-cell activation is of predictive effect on CD4+ T-cell recovery.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/e9yz-dc87

Authors: Bosch, Ronald J., Hammer, Scott M., Zhang, Xinyan, Patterson, Kristine B., Hunt, Peter W., Cespedes, Michelle S.

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Awards: G1033683653, G115468880, G2027736814