Development and Validation of a Symptom-Based Activity Index for Adults With Eosinophilic Esophagitis
Year: 2020
Type: article
Abstract: Standardized instruments are needed to assess the activity of eosinophilic esophagitis (EoE), to provide endpoints for clinical trials and observational studies. We aimed to develop and validate a patient-reported outcome (PRO) instrument and score, based on items that could account for variations in patients’ assessments of disease severity. We also evaluated relationships between patients’ assessment of disease severity and EoE-associated endoscopic, histologic, and laboratory findings.
DOI: 10.17615/edkm-4w79
Authors: Leung, John, Locke, G. Richard, Drouin, Eric, Gonsalves, Nirmala, Spergel, Jonathan M., Wu, Tsung Teh, Alexander, Jeffrey A., Yang, Guang Yu, Chehade, Mirna, Maurer, Elisabeth, Dellon, Evan S., Aceves, Seema S., Butterfield, Joseph H., Krishna, Murli, Hirano, Ikuo, Crowell, Michael D., Gupta, Sandeep K., Straumann, Alex, Netzer, Peter, Zwahlen, Marcel, Armstrong, David, Kita, Hirohito, Kern, Emily, Taft, Tiffany H., Orbelo, Diana M., Yost, Kathleen J., De Petris, Giovanni, Katzka, David A., DeVault, Kenneth R., Lim, Kaiser, Ramirez, Francisco C., Lewis, John C., Guyatt, Gordon H., Moawad, Fouad J., Haas, Nadine A., Francis, Dawn L., Arora, Amindra S., Safroneeva, Ekaterina, Woosley, John T., Panczak, Radoslaw, Foxx-Orenstein, Amy, Enders, Felicity T., Harris, Lucinda A., Nguyen, Cuong C., Kagalwalla, Amir F., Murray, Joseph A., Achem, Sami R., Furuta, Glenn T., Lee, James J., Enav, Benjamin, Bussmann, Christian, Schoepfer, Alain M., Pasha, Shabana F., Sheikh, Javed, Collins, Margaret H., Romero, Yvonne, Fleischer, David E., Smyrk, Thomas C., Wo, John M., Attwood, Stephen E., Coslovsky, Michael, Yan, Pu, Alpan, Oral, Umar, Sarah B., Kuehni, Claudia E., Weiler, Catherine R.
Institution: University of North Carolina at Chapel Hill
Language: English
Topic: Eosinophilic Esophagitis
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4302070028