Work

TfR Aptamer Enhanced Blood‐Brain Barrier Penetration of Biomimetic Nanocomplexes for Intracellular Transglutaminase 2 Imaging and Silencing in Glioma (Small 40/2022)

Year: 2022

Type: article

Abstract: Brain Tumor Theranostics In article number 2203448, Hongping Xia, Songqin Liu, Yafeng Wu, and co-workers prepare dual blood–brain barrier (BBB) targeting biomimetic nanocomplexes (TMPsM) for simultaneous accurate diagnosis and effective treatment of glioma. The biomimetic outer shells endow them with enhanced BBB penetration and ensure the delivery of theranostic agents into brain tumor sites for single intracellular transglutaminase 2-triggered self-assembly aggregation-induced emission imaging and RNAi therapy.

Source: Small

DOI: 10.1002/smll.202270212

Authors: Juan Su, Zhipeng Yao, Zixuan Chen, Sisi Zhou, Zhi Wang, Hongping Xia, Songqin Liu, Yafeng Wu

Institutions: State Key Laboratory of Digital Medical Engineering, Southeast University, Wannan Medical College, First Affiliated Hospital of Wannan Medical College, Wuxi Municipal Product Quality Supervision and Inspection Institute

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4302288138

FWCI:

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