Work

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

Year: 2010

Type: review

Source: Nature reviews. Cancer

DOI: 10.1038/nrc2960

Authors: Dominico Vigil, Jacqueline Cherfils, Kent L. Rossman, Channing J. Der

Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Centre National de la Recherche Scientifique, Laboratoire d'Enzymologie et Biochimie Structurales

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Cancer Society, Centre National de la Recherche Scientifique, National Institutes of Health, Gillings School of Public Health, National Cancer Institute

Awards: Mechanism and role of DLC-1 tumor suppressor loss in lung cancer, G1299876681, G2089382142, Rho Family Proteins and Malignant Transformation, G2978045611, Biological Activity of Ras Oncogenes, G5028106406, SPORE in Gastrointestinal Cancer, Inhibitors of Rho function as novel cancer therapeutics, Role of RGS proteins in Ras- and B-Raf--mediated transformation, G8852992010, G9000071908, G9000174629, G9000329203, G970245308

OpenAlex ID: W2071018921

FWCI: 4.266

Cites: 181

Cited by: 816

Related to: 10