Standard Operating Procedures for Biospecimen Collection, Processing, and Storage
Year: 2022
Type: article
Abstract: ABSTRACT: Differences in methods for biospecimen collection, processing, and storage can yield considerable variability and error. Therefore, best practices for standard operating procedures are critical for successful discovery, development, and validation of disease biomarkers. Here, we describe standard operating procedures developed for biospecimen collection during the DREAM (Diabetes RElated to Acute pancreatitis and its Mechanisms) Study within the Type 1 Diabetes in Acute Pancreatitis Consortium. Notably, these protocols were developed using an integrative process based on prior consortium experience and with input from working groups with expertise in immunology, pancreatitis, and diabetes. Publication and adoption consistent biospecimen protocols will inform future studies and allow for better comparisons across different metabolic research efforts.
Source: Pancreas
Authors: Clive Wasserfall, Anne-Marie Dyer, Cate Speake, Dana K. Andersen, Kendall Thomas Baab, Melena D. Bellin, James R. Broach, Martha Campbell-Thompson, Vernon M. Chinchilli, Peter J. Lee, Walter G. Park, Richard E. Pratley, Jami L. Saloman, Emily K. Sims, Gong Tang, Dhiraj Yadav, Cemal Yazici, Darwin L. Conwell
Institutions: University of Florida Health, University of Florida, Pennsylvania State University, Benaroya Research Institute, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, University of Minnesota, The Ohio State University Wexner Medical Center, Stanford Medicine, Stanford University, AdventHealth Orlando, AdventHealth, University of Pittsburgh, Indiana University School of Medicine, University of Illinois Chicago
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Neuropathic vs. inflammatory pain in chronic pancreatitis: can unique biomarkers be identified to guide mechanistic approaches to pain treatment?, Understanding pancreatic endocrine and exocrine loss in pre-type 1 diabetes, Institutional Career Development, Mechanism-based Approach to Pain in Chronic Pancreatitis (MAP-CP Study), UPMC Clinical Center for the Study of Diabetes after Acute Pancreatitis, The Stanford Clinical Center for the Study of Type 1 Diabetes in Acute Pancreatitis, Epidemiology and Pathophysiology of Acute Pancreatitis-related Diabetes Mellitus, Cedars Sinai Clinical Center of the Type 1 Diabetes in Acute Pancreatitis Consortium, Type 1 Diabetes in Acute Pancreatitis Consortium – Pacific Northwest Clinical Center: Immune Pathogenesis of Post-Pancreatitis T1D, Mechanisms of diabetes from acute pancreatitis in African Americans and Hispanics, University of Minnesota Clinical Center for the Study of Acute Pancreatitis and Diabetes, The Chronic Pancreatitis Clinical Research Consortium, Indiana Diabetes Research Center, Data Coordinating Center for the Type 1 Diabetes in Acute Pancreatitis Consortium, Continuation of Type 1 Diabetes in Acute Pancreatitis Consortium – UF Health and AdventHealth Combined Clinical Center, Clinical, Radiologic and Biochemical Factors Related to Diabetes Development after Acute Pancreatitis, Indiana University clinical Center for acute pancreatitis and diabetes clinical research network
OpenAlex ID: W4303684912