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Neuronal ambient RNA contamination causes misinterpreted and masked cell types in brain single-nuclei datasets

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Year: 2022
Type: article
Source: Neuron
DOI: 10.1016/j.neuron.2022.09.010
Authors: Emre Caglayan, Yuxiang Liu, Genevieve Konopka
Institution: The University of Texas Southwestern Medical Center
Language: English

Topic: Single-cell and spatial transcriptomics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: James S. McDonnell Foundation, American Heart Association, University of Texas Southwestern Medical Center, National Institute of Mental Health, National Human Genome Research Institute, National Institute of Neurological Disorders and Stroke
Awards: Functional studies of CLOCK in brain health, From ion channels to graph theory in sensorimotor learning, Comparative Epigenomics of Primate Brains, Human Specific Brain DNA Methylation and Neuropsychiatric Diseases, Foxp-regulated signaling pathways in brain development
OpenAlex ID: W4305016438
FWCI: 7.059
Cites: 59
Cited by: 127
Related to: 10
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