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Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells

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Year: 2022
Type: article
Source: Cancer Cell
DOI: 10.1016/j.ccell.2022.09.013
Authors: Xingying Zhang, Chenze Zhang, Miaomiao Qiao, Chen Cheng, Na Tang, Shan Lu, Wen Sun, Beilei Xu, Yuanwei Cao, Xiaofei Wei, Yao Wang, Weidong Han, Haoyi Wang
Institutions: Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Zoology, State Key Laboratory of Stem Cell and Reproductive Biology, University of Science and Technology of China, Chinese PLA General Hospital, Beijing Institute for Stem Cell and Regenerative Medicine
Language: English

Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Guangzhou Medical University, National Natural Science Foundation of China, Chinese Academy of Sciences, Ministry of Science and Technology of the People's Republic of China, National Key Research and Development Program of China
Awards: G2101884534, G2496217894, G4075202727, G8099200914, G8848910528
OpenAlex ID: W4306155265
FWCI: 14.12
Cites: 78
Cited by: 175
Related to: 10
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