Work

LncRNA UCA1 accelerates osteosarcoma progression via miR-145 and Wnt/β-catenin pathway.

Year: 2022

Type: article

Abstract: . Moreover, the DLR assay and RNA immunoprecipitation (RIP) showed that UCA1 was likely to regulate HMGA1 levels by sponging miR-145. Overall, the inhibition of UCA1 increases miR-145 levels and decreases HMGA1 levels, thereby exerting an anti-tumor role in OS.

Source: PubMed

Authors: Jian Guan, Juliang He, Shian Liao, Zhenjie Wu, Xiang Lin, Bin Liu, Xiong Qin, Jiachang Tan, Chuangming Huang, Zhenchao Yuan, Hao Mo

Institutions: Guangxi Medical University, Tumor Hospital of Guangxi Medical University

Language: English

Topic: Cancer-related molecular mechanisms research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4306667737

FWCI: 0.262

Cites: 42

Cited by: 3

Related to: 10