Work

Listeria monocytogenes Co-Opts the Host Exocyst Complex To Promote Internalin A-Mediated Entry

Year: 2022

Type: article

Abstract: The bacterial pathogen Listeria monocytogenes induces its internalization (entry) into intestinal epithelial cells through interaction of its surface protein, internalin A (InlA), with the human cell-cell adhesion molecule, E-cadherin. While InlA-mediated entry requires bacterial stimulation of actin polymerization, it remains unknown whether additional host processes are manipulated to promote internalization.

Source: Infection and Immunity

DOI: 10.1128/iai.00326-22

Authors: Gaurav Chandra Gyanwali, Thilina U. B. Herath, Antonella Gianfelice, Keith Ireton

Institution: University of Otago

Language: English

Topic: Listeria monocytogenes in Food Safety

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Ministry of Health, New Zealand, Maurice and Phyllis Paykel Trust, Health Research Council of New Zealand