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Author response: Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity

Year: 2022
Type: peer-review
Abstract: Machine learning-assisted experiments reveal CD81 as a novel binding partner of CD44 in driving cancer stemness, tumor cell clustering, and extracellular vesicle integrity in human and mouse breast cancer.
DOI: 10.7554/elife.82669.sa2
Authors: Erika K Ramos, Chia-Feng Tsai, Yuzhi Jia, Yue Cao, Megan Manu, Rokana Taftaf, Andrew D Hoffmann, Lamiaa El-Shennawy, Marina A Gritsenko, Valery Adorno-Cruz, Emma J Schuster, David Scholten, Dhwani Patel, Xia Liu, Priyam Patel, Brian Wray, Youbin Zhang, Shanshan Zhang, Ronald J Moore, Jeremy V Mathews, Matthew J Schipma, Tao Liu, Valerie L Tokars, Massimo Cristofanilli, Tujin Shi, Yang Shen, Nurmaa K Dashzeveg, Huiping Liu
Institutions: Northwestern University, Pacific Northwest National Laboratory, Texas A&M University, University of Kentucky, Northwestern University, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
OpenAlex ID: W4306804809
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