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Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death

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Year: 2022
Type: article
Source: Nature Chemical Biology
DOI: 10.1038/s41589-022-01170-9
Authors: Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin Garvie, Joseph McGaunn, Mrinal Shekhar, Marcus Tötzl, Matthew G. Rees, Andrew D. Cherniack, Matthew Meyerson, Heidi Greulich
Institutions: Broad Institute, Dana-Farber Cancer Institute
Language: English

Topic: RNA and protein synthesis mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute
Awards: G4376379040, Lung Adenocarcinoma: From Genome Alterations to Therapeutic Discovery, G663659838, G913518808
OpenAlex ID: W4307501844
FWCI: 2.21
Cites: 44
Cited by: 40
Related to: 10
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