Work

A Malignant Glomus Tumor of the Liver Harboring MIR143-NOTCH2 Rearrangement: From Diagnosis to Management

Year: 2022

Type: article

Abstract: A primary malignant glomus tumor of the liver is extremely rare and diagnostically challenging. We present an exceptional case of such with a diagnosis confirmed by MIR143-NOTCH2 rearrangement. The case was successfully managed with neoadjuvant chemotherapy followed by surgery. This report highlights the utilization of molecular analysis to aid in the diagnosis of rare soft tissue malignancies and supports a multimodality approach to the treatment of large, high-grade malignant glomus tumors.

Source: Cureus

DOI: 10.7759/cureus.30718

Authors: Ruoyu Miao, Marilyn M Bui, Christine Walko, John E Mullinax, Andrew S Brohl

Institution: Moffitt Cancer Center

Language: English

Topic: Soft tissue tumors and treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4307545074