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Neisseria meningitidis serogroup A capsular polysaccharide acetyltransferase, methods and compositions

Year: 2023

Type: article

Abstract: Provided are methods for recombinant production of an O-acetyltransferase and methods for acetylating capsular polysaccharides, especially those of a Serogroup A Neisseria meningitidis using the recombinant O-acetyltransferase, and immunogenic compositions comprising the acetylated capsular polysaccharide.

Source: OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

Author: Stephens, David S [Stone Mountain, GA]; Gudlavalleti, Seshu K [Kensington, MD]; Tzeng, Yih-Ling [Atlanta, GA]; Datta, Anup K [San Diego, CA]; Carlson, Russell W [Athens, GA]

Language: English

Topic: Bacterial Infections and Vaccines

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4307618525

FWCI:

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Related to: 10