Work

An MDM2 degrader for treatment of acute leukemias

Year: 2022

Type: article

Source: Leukemia

DOI: 10.1038/s41375-022-01735-6

Authors: Bridget K. Marcellino, Xiaobao Yang, H. Ümit Kaniskan, Claudia Brady, He Chen, Karie Chen, Xing Qiu, Cara Clementelli, Lauren Herschbein, Zhijun Li, Sebastian Elghaity-Beckley, Joann Arandela, Brianna Kelly, Ronald Hoffman, Jing Liu, Yue Xiong, Jian Jin, Alan H. Shih

Institutions: Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, University of North Carolina at Chapel Hill

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Gilead Sciences, MPN Research Foundation, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: An AVANCE NEO 600 MHz NMR Spectrometer System for Structural and Chemical Biology, Maintaining Genome Integrity and Suppressing Tumorigenesis by the 3M-CUL7-CUL9-p53, An AVANCE NEO 400 MHz NMR Spectrometer for Chemical Biology and Drug Discovery, G803893432

OpenAlex ID: W4307657940

FWCI: 1.588

Cites: 37

Cited by: 35

Related to: 10