Work

Radioisotope trithiol complexes

Year: 2023

Type: article

Abstract: The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.

Source: OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

Author: Jurisson, Silvia S.; Cutler, Cathy S.; Degraffenreid, Anthony J.

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W4307675748

FWCI:

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Related to: 10