Work

Cysteine-Dependent Conformational Heterogeneity of Shigella flexneri Autotransporter IcsA and Implications of Its Function

Year: 2022

Type: article

Abstract: Shigella species are the leading cause of diarrheal-related death globally by causing bacillary dysentery. The surface virulence factor IcsA, which is essential for Shigella pathogenesis, is a unique multifunctional autotransporter that is responsible for cell adhesion, and actin-based motility, yet detailed mechanistic understanding is lacking.

Source: Microbiology Spectrum

DOI: 10.1128/spectrum.03410-22

Authors: Jilong Qin, Yaoqin Hong, Renato Morona, Makrina Totsika

Institutions: Queensland University of Technology, The University of Adelaide

Language: English

Topic: Escherichia coli research studies

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500