Work

Coordination Stoichiometry Effects on the Binding Hierarchy of Histamine and Imidazole–M 2+ Complexes

Year: 2023

Type: article

Abstract: Histidine–M 2+ coordination bonds are a recognized bond motif in biogenic materials with high hardness and extensibility, which has led to growing interest in their use in soft materials for mechanical function. However, the effect of different metal ions on the stability of the coordination complex remains poorly understood, complicating their implementation in metal‐coordinated polymer materials. Herein, rheology experiments and density functional theory calculations are used to characterize the stability of coordination complexes and establish the binding hierarchy of histamine and imidazole with Ni 2+ , Cu 2+ , and Zn 2+ . It is found that the binding hierarchy is driven by the specific affinity of the metal ions to different coordination states, which can be macroscopically tuned by changing the metal‐to‐ligand stoichiometry of the metal‐coordinated network. These findings facilitate the rational selection of metal ions for optimizing the mechanical properties of metal‐coordinated materials.

Source: Macromolecular Rapid Communications

DOI: 10.1002/marc.202300077

Authors: Jake Song, Eesha Khare, Li Rao, Markus J Buehler, Niels Holten‐Andersen

Institutions: Massachusetts Institute of Technology, Central China Normal University, Lehigh University

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,120