Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Work
Year: 2022
Type: article
Abstract: The mammalian SWItch/Sucrose Non-Fermentable (SWI/SNF) helicase SMARCA4 is frequently mutated in cancer and inactivation results in a cellular dependence on its paralog, SMARCA2, thus making SMARCA2 a... more
Source: Nature Communications
Institution Arvinas (United States)
Cites: 43
Cited by: 76
Related to: 10
FWCI: 8.41
Citation percentile (by year/subfield): 100
Subfield: Molecular Biology
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: gold
APC paid (est): $4,808