OXPHOS promotes apoptotic resistance and cellular persistence in T H 17 cells in the periphery and tumor microenvironment
Work
Year: 2022
Type: article
Abstract: T cell proliferation and cytokine production are bioenergetically and biosynthetically costly. The inability to meet these metabolic demands results in altered differentiation, accompanied by impaired... more
Source: Science Immunology
Institutions University of Michigan, Michigan State University, Inserm, Centre d’Immunologie de Marseille-Luminy, Centre National de la Recherche Scientifique
Cites: 59
Cited by: 50
Related to: 10
FWCI: 7.565
Citation percentile (by year/subfield): 81.48
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green