Work

Silica nanoparticle remodeling under mild conditions: versatile one step conversion of mesoporous to hollow nanoparticles with simultaneous payload loading

Year: 2022

Type: article

Abstract: A binary mixture of mesoporous silica nanoparticles plus organic polyammonium additive (dye or drug) is cleanly converted upon mild heating into hollow nanoparticles. The remodeled nanoparticle shell is an organized nanoscale assembly of globular additive/silica subunits and cancer cell assays show that a loaded drug additive is bioavailable.

Source: Nanoscale

DOI: 10.1039/d2nr05528g

Authors: Cassandra C. Shaffer, Canjia Zhai, Jordan L. Chasteen, Tatyana Orlova, Maksym Zhukovskyi, Bradley D. Smith

Institution: University of Notre Dame

Language: English

Topic: Mesoporous Materials and Catalysis

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, National Institute of General Medical Sciences