Work

Targeting PI3Kα overcomes resistance to KRasG12C inhibitors mediated by activation of EGFR and/or IGF1R

Year: 2022

Type: article

Source: Acta Pharmacologica Sinica

DOI: 10.1038/s41401-022-01015-0

Authors: Wei-liang Qi, Hui-yu Li, Yi Wang, Lan Xu, Jie-ting Deng, Xi Zhang, Yu-xiang Wang, Ling-hua Meng

Institutions: Nanchang University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Nanjing University of Chinese Medicine

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality

Awards: G227312276, G3648743189, G7862910479, G8153545879

OpenAlex ID: W4309656491

FWCI: 1.177

Cites: 44

Cited by: 20

Related to: 10