Weight Status of Children Participating in the National Spina Bifida Patient Registry
Year: 2022
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: Describe the distribution of weight status categories and determine factors associated with overweight and obesity (OW/OB) in children and adolescents with spina bifida (SB) using the National Spina Bifida Patient Registry. METHODS: Demographic, anthropometric, and clinical data collected from 2009 through 2018 was used to describe the prevalence of OW/OB. The generalized estimating equation model (GEE) identified factors associated with OW/OB among individuals with SB. RESULTS: Participants (n = 7215) were aged 2 to 19 years (mean = 11.1; standard error, 0.06) and 51.4% female. The majority were non-Hispanic white (57.2%) followed by Hispanic or Latino (25.1%) and non-Hispanic Black (7.5%). The myelomeningocele (MMC) subgroup accounted for 76.3%. Most (60.2%) were community ambulators. The overall percentage of OW/OB was 45.2%, with 49.2% of MMC and 32.0% of nonmyelomeningocele OW/OB. Following the Centers for Disease Control Obesity Severity Classification System, 19.7% of MMC were in class 1, 6.6% in class 2, and 3.5% in class 3. Univariate analysis of MMC participants demonstrated demographic (age, sex, race/ethnicity, and clinic region) and clinical variables (functional level of lesion, ambulation, and number of shunt surgeries) were associated with OW/OB. The GEE model showed that OW/OB was independently, and significantly, associated with age, sex, race/ethnicity, lesion levels, and geographic location of the clinics. CONCLUSIONS: The demographic and clinical factors associated with OW/OB in children and adolescents with SB further our understanding of factors contributing to the higher prevalence of OW/OB in this population and may inform OW/OB prevention and treatment strategies.
Source: PEDIATRICS
Institutions: Children's Hospital of Wisconsin, University of Wisconsin–Milwaukee, Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, University of Southern California, Children's Hospital Los Angeles, Spina Bifida Association, SUNY Upstate Medical University
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: COMP B-OREGON SPINA BIFIDA REGISTRY PROJECT, NATIONAL SPINA BIFIDA PATIENT REGISTRY, COMP B-SEATTLE CHILDREN'S CARE AND OUTCOMES REGISTRY FOR SPINA BIFIDA, GREATER SAN FRANCISCO BAY AREA SPINA BIFIDA PARTNERSHIP, COMP B-NATIONAL SB PATIENT REGISTRY AT VANDERBILT CHILDREN'S HOSPITAL, NATIONAL SPINA BIFIDA REGISTRY LONGITUDINAL DATA COLLECTION AND EVALUATION, COMP B-IMPROVING CARE OF WISCONSIN RESIDENTS LIVING WITH SPINA BIFIDA: THE NSBPR, COMP B-NATIONAL SPINA BIFIDA REGISTRY-LURIE CHILDREN'S HOSPITAL, COMP B-NATL SB PATIENT REGISTRY AND UROLOGIC MANAGEMENT OF YOUNG CHILDREN WITH SB- DUKE PROJECT, COMP B-TEXAS CHILDREN'S HOSPITAL AND BAYLOR COLL OF MED SPINA BIFIDA REGISTRY, COMP B-NATIONAL SPINA BIFIDA PATIENT REGISTRY, COMP B-SB PATIENT REGISTRY PROJECT AT RILEY HOSPITAL FOR CHILDREN, RESEARCH APPROACHES TO IMPROVING THE CARE AND OUTCOMES OF PEOPLE LIVING WITH SPINA BIFIDA IN WISCONSIN: THE NSBPR, COMP B-PARTICIPATION OF GILLETTE CHILDREN'S SPECIALTY HEALTHCARE IN THE NSBPR, PENN STATE SPINA BIFIDA CLINIC REGISTRY DEMONSTRATION PROJECT, COMP B-PRIMARY CHILDREN'S HOSPITAL SPINA BIFIDA PATIENT REGISTRY, NATIONAL SBA REGISTRY DEMONSTRATION PROJECT 2, COMP B-NATIONAL SB PATIENT REGISTRY AT THE UNIVERSITY OF PITTSBURGH, COMP B-RESEARCH APPROACHES TO IMPROVE THE CARE AND OUTCOMES OF PEOPLE LIVING WITH SB, NATIONAL SPINA BIFIDA PATIENT REGISTRY, G7543494365, COMP B-IMPROVING THE CARE AND OUTCOMES OF PEOPLE LIVING WITH SB
OpenAlex ID: W4309721274