Work

Author response: A general approach for stabilizing nanobodies for intracellular expression

Year: 2022

Type: peer-review

Abstract: A large proportion of nanobodies are unstable when expressed intracellularly, but can be reliably stabilized for intracellular expression by applying a generalizable mutagenesis strategy based on positional sequence conservation.

Source: eLife

DOI: 10.7554/elife.68253.sa2

Authors: John G Dingus, Jonathan CY Tang, Ryoji Amamoto, Grace K Wallick, Constance L Cepko

Institutions: Howard Hughes Medical Institute, Harvard University

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4309792867

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