Work

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

Year: 2022

Type: article

Source: Blood

DOI: 10.1182/blood-2022-162782

Authors: V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll, Christian Hurtz

Institutions: Temple University, Children's Hospital of Philadelphia, University of Pennsylvania, City of Hope, Beckman Research Institute, Hospital of the University of Pennsylvania, Centre National de la Recherche Scientifique, Laboratoire COBRA, Université de Rouen Normandie, Institut National des Sciences Appliquées Rouen Normandie, St. Jude Children's Research Hospital

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4310096179

FWCI: 0.202

Cites:

Cited by: 1

Related to: 10