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Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Year: 2022
Type: article
Source: Blood
DOI: 10.1182/blood-2022-162639
Authors: Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Guolian Kang, Cicera Lazzarotto, Yichao Li, Rachel Levine, Erin Dempsey, Shaina N. Porter, Phillip A Doerfler, Jingjing Zhang, Yoonjeong Jang, Senthil Bhoopalan, Nikitha Nimmagadda, Akshay Sharma, John Tisdale, Shondra Miller, Yong Cheng, Shengdar Tsai, Mitchell J. Weiss, David R. Liu, Jonathan S Yen
Institutions: St. Jude Children's Research Hospital, Broad Institute, Harvard University, Massachusetts Institute of Technology, National Institutes of Health, National Heart, Lung, and Blood Institute, Howard Hughes Medical Institute
Language: English
Subfield: Genetics
Field: Medicine
Open Access status: closed
OpenAlex ID: W4310109037
FWCI: 0.127
Cites:
Cited by: 1
Related to: 10