Work

Author response: Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections

Year: 2022

Type: peer-review

Abstract: Cryo-electron microscopy can be used to detect biomolecules in entire 100- to 250-nm-thick cell slices when using a method to collect montages that prevents radiation damage in areas that have not been imaged yet.

Source: eLife

DOI: 10.7554/elife.80980.sa2

Authors: Johannes Elferich, Giulia Schiroli, David T Scadden, Nikolaus Grigorieff

Institutions: Howard Hughes Medical Institute, University of Massachusetts Chan Medical School, Harvard University, Massachusetts General Hospital, Harvard Stem Cell Institute

Language: English

Topic: Advanced Electron Microscopy Techniques and Applications

Subfield: Structural Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4310437743

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