Work

Burning down the house: reinventing drug discovery in psychiatry for the development of targeted therapies

Year: 2022

Type: review

Source: Molecular Psychiatry

DOI: 10.1038/s41380-022-01887-y

Authors: Andrew H. Miller, Charles L. Raison

Institutions: Emory University, University of Wisconsin–Madison

Language: English

Topic: Treatment of Major Depression

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, National Center for Advancing Translational Sciences

Awards: Inflammation-Induced CNS Glutamate Changes in Depression, G2403874655, G3825745767, G4137819231, G4171796331, G4468166784, G4478057528, Effects of Bupropion versus Escitalopram on Reward Circuitry and Motivational Deficits in Patients with Major Depression and Increased Inflammation and Anhedonia, Effects of the Next Generation TNF Inhibitor (XPro1595) on Inflammation-related Deficits in Reward Circuitry and Motivation in Depression, Using Human iPSC Models to Determine the Mechanism of Inflammation-Induced Disruption of Dopamine Neurotransmission, The Role of Inflammation in CNS Mechanisms of Anhedonia and Psychomotor Slowing in Depressed PWH as Determined using a Next Generation TNF Antagonist, Georgia Clinical & Translational Science Alliance (Georgia CTSA)

OpenAlex ID: W4310644014

FWCI: 1.815

Cites: 97

Cited by: 72

Related to: 10