Year: 2022
Type: review
Abstract: Negative results can be a source of disappointment for scientists, yet their publication is needed for scientific progress, in particular for cutting-edge translational research of novel therapeutics. This manuscript is directed to scientists, junior and senior, that produce and review data for publication. It discusses the difference between 'negative' or 'unexpected' data and 'useless' data, re-evaluates the importance of the experimental design to generate valuable data and proposes strategies to work with and report negative results. Overall, it aims to reframe the perception of working with, reporting and reviewing unexpected data as an opportunity to provide rationale for innovative ideas, prevent the misuse of limited resources and, ultimately, strengthen the reputation of a scientist.
Source: Brain Research Bulletin
Author: Marina E. Emborg
Institution: University of Wisconsin–Madison
Language: English
Subfield: Library and Information Sciences
Field: Social Sciences
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $3,090
Awards: Enhancing the marmoset aging model through biomarker development, G1667978519, G194610825, G3063950600, Modeling Frontotemporal Dementia in Rhesus Macaques, G5150790795, Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain, Wisconsin National Primate Research Center Support
OpenAlex ID: W4311661990