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Engineered Human Antibody with Improved Endothelin Receptor Type A Binding Affinity, Developability, and Serum Persistence Exhibits Excellent Antitumor Potency

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Year: 2022
Type: article
Source: Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.2c00923
Authors: Sanghwan Ko, Man-Seok Ju, Hye-Mi Ahn, Jung-Hyun Na, Woo Hyung Ko, Migyeong Jo, Munsu Kyung, Chung Su Lim, Byoung Joon Ko, Won-Kyu Lee, Youn-Jae Kim, Sang Taek Jung
Institutions: Korea University, National Cancer Center, Sangji University, Osong Medical Innovation Foundation, Sungshin Women's University
Language: English

Topic: Monoclonal and Polyclonal Antibodies Research
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Cancer Center, National Research Foundation of Korea
Awards: G2579467062, G3340247035, G3737561125, G4886075403, G5702789435
OpenAlex ID: W4312129020
FWCI: 0.187
Cites: 42
Cited by: 3
Related to: 10
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