Year: 2022
Type: editorial
Abstract: Editorial on the Research Topic Innovation and transformation of chronic airway diseasesChronic airway disease, including chronic obstructive pulmonary disease (COPD), bronchial asthma, bronchiectasis, and other pulmonary disease, is a common respiratory disease worldwide (Soriano et al., 2020, 8(6), 585-596).COPD was the third leading cause of death worldwide, causing the death of 3.23 million people (WHO, 2019), which has become a huge global burden (Quaderi and Hurst, 2018, 3, e4).In this context, numerous efforts have been made with the aim of identifying the mechanism of these diseases, exploring effective prevention measures and therapeutic strategies.In particular, innovation and transformation of chronic airway diseases should be worthy of attention.To date, the mechanism of chronic airway disease is not completely understood (Barnes Peter, 2017).Nonetheless, diverse researches have shown great advances, which may bring more efficient therapy of these diseases.Despite this, more innovation is necessary for us to solve the problems in treatment and prevention of chronic airway diseases.This Research Topic aims to collect innovation and transformation research in fields related to the pathogenesis and treatment of chronic airway diseases, to provide new alternatives for early diagnosis and treatment of chronic airway diseases.In this Research Topic, Qiao et al. reviewed the regulator roles of the lncRNA -miRNA -mRNA network in different cell types and their potential as the biomarkers or therapeutic targets of chronic inflammatory airway diseases (Qiao et al.).Several lncRNAs acting as miRNA sponges in different cells, such as bronchial epithelial cells, pulmonary microvascular endothelial cells and T Lymphocytes, have been focused in chronic airway diseases.The cross-talk among lncRNAs, miRNAs and mRNAs is involved in the pathophysiology of chronic inflammatory airway diseases.Meanwhile, Jiang and Chen summarized and analyzed the biological functions and mechanisms of sulfur compounds in regulating COPD and its comorbidities (Jiang and Chen).Sulfur compounds have the potential to protect individuals from developing chronic
Authors: Rui Zhao, Yan Chen, Yiming Ma, Chunbin Zou, Jing Zhang, Zhihua Chen
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,950
OpenAlex ID: W4312138163