Synthesis and spectral properties of pH probes based on imidazopyridine
Year: 2019
Type: article
Abstract: In order to obtain a pH fluorescent probe suitable for extremely acidic environment, we use imidazo [1, 2-a] pyridine compounds as receptors and double bonds as bridge-connected donor phenothiazine to synthesize a compound 10-(2-(2-methoxyethoxy)ethyl-3-(2-(2-phenylimidazo [1, 2-a] pyridin-7-yl)vinyl)-10H-phenothiazine. The results of pH titration show that with the pH decrease from 7.0 to 0.4, the UV absorption intensity of the compound gradually reduces at 399 nm but gradually increases at 419 nm, and the fluorescence emission peak intensity gradually reduces at 573 nm. The pKa of the compound is 3.07. The synthesized compound can be used as a new pH fluorescent probe suitable for extremely acidic environment.
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4312753640