Work

Towards a primate single-cell atlas

Year: 2022

Type: article

Abstract: NHP cell atlas composed of single-cell/single-nucleus transcriptomes of 1.14 million cells (nuclei), covering 113 major cell types across 45 tissues. Cross-tissue comparison of cell types and molecular features revealed tissue specificity in common cell types, cellular vulnerability to COVID-19, tissue stem cells, and cell-type association with complex human traits and monogenic heritable diseases. The monkey drawing was generated by Ming-Jiang Lu and Rui Zeng (BGI-Shenzhen). Part of this diagram was drawn using free-to-use artwork from Servier Medical Art (https://smart.servier.com/).

Source: 动物学研究

DOI: 10.24272/j.issn.2095-8137.2022.212

Authors: Xiao Zhang, Guang-Yao Lai, Giacomo Volpe, Lei Han, Patrick H. Maxwell, Long-Qi Liu, Miguel A. Esteban, Yi-Wei Lai, Hematology and Cell Therapy Unit, IRCCS-Istituto Tumori ‘Giovanni Paolo II’, Bari 70124, Italy, BGI-Shenzhen, Shenzhen, Guangdong 518103, China

Institutions: Jilin University, Guangzhou Institutes of Biomedicine and Health, Guangzhou Medical University, Istituto Tumori Bari, BGI Group (China), University of Cambridge, Chinese Academy of Sciences

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W4285586705

FWCI: 0.653

Cites: 21

Cited by: 9

Related to: 10