Work

Human Tooth as a Fungal Niche: Candida albicans Traits in Dental Plaque Isolates

Year: 2023

Type: article

Abstract: Severe early childhood caries is a widespread global public health problem causing extensive tooth decay and systemic complications. Candida albicans , a fungus typically found in mucosal surfaces, is frequently detected in dental plaque formed on teeth of diseased toddlers. However, the clinical traits of C. albicans isolated from tooth remain underexplored.

Source: mBio

DOI: 10.1128/mbio.02769-22

Authors: Zhenting Xiang, Rohan S. Wakade, Apoena Aguiar Ribeiro, Weiming Hu, Kyle Bittinger, Aurea Simon-Soro, Dongyeop Kim, Jiyao Li, Damian J. Krysan, Yuan Liu, Hyun Koo

Institutions: Sichuan University, State Key Laboratory of Oral Diseases, University of Pennsylvania, University of Iowa, University of North Carolina at Chapel Hill, Children's Hospital of Philadelphia, Universidad de Sevilla, Jeonbuk National University

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: Colgate-Palmolive Company, National Institute of Allergy and Infectious Diseases, National Institute of Dental and Craniofacial Research

Awards: G1325150386, S. mutans-C. albicans interactions synergize the virulence of cariogenic biofilms, G4767457937, Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis

OpenAlex ID: W4313544757

FWCI: 7.443

Cites: 59

Cited by: 38

Related to: 10