National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso
Year: 2023
Type: article
Abstract: Malaria due to the Plasmodium falciparum parasite remains a threat to human health despite eradication efforts and the development of anti-malarial treatments, such as artemisinin combination therapies. Human movement and migration have been linked to the propagation of malaria on national scales, highlighting the need for the incorporation of human movement in modeling efforts. Spatially couped individual-based models have been used to study how anti-malarial resistance evolves and spreads in response to drug policy changes; however, as the spatial scale of the model increases, the challenges associated with modeling of movement also increase. In this paper we discuss the development, calibration, and validation of a movement model in the context of a national-scale, spatial, individual-based model used to study the evolution of drug resistance in the malaria parasite.
Source: Scientific Reports
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,390
Awards: G2937666008, Disease Emergence and Elimination: Using Mobility Data to Inform Spatial Disease Dynamics, Penn State - to use mathematical modelling approaches to understand the emergence of antimalarial drug resistance, including in the context of multiple first-li..., Northwestern University - to use mathematical models for country-level stratification and intervention planning to accelerate countries towards malaria elimination, G6233911319, G9000085867, Human mobility models to forecast disease dynamics and the effectiveness of public health interventions
OpenAlex ID: W4313650673