Association of Ambient and Household Air Pollution with Lung Function in Young Adults in an Peri-urban Area of South-India: a cross-sectional study
Year: 2022
Type: conference-abstract
Abstract: BACKGROUND AND AIM: Although there is evidence for the association between air pollution and decreased lung function in children, evidence for adolescents and young adults is scarce. For a peri-urban area in India, we evaluated the association of ambient and household air pollution with lung function for young adults who had recently attained their expected maximum lung function. METHODS: We measured, using a standardized protocol, forced expiratory volume in the first second (FEV₁) and forced vital capacity (FVC) in participants aged 20-26 years from the third follow-up of the population-based APCAPCS cohort (2010-2012) in 28 Indian villages. We estimated annual average PM₂.₅ outdoors at residence using land-use regression. Biomass cooking fuel (a proxy for levels of household air pollution) was self-reported. We fitted a within-between linear-mixed model with random intercepts by village, adjusting for potential confounders. RESULTS: We evaluated 1,044 participants with mean age of 22.8 (SD=1) years (p25-p75: 22-24); 327 participants (31%) were female. Only males reported use of tobacco smoking (9% of all participants, 13% of males). The mean ambient PM2.5 exposure was 32.9 (SD=2.8) µg/m³. 76% reported use of biomass as cooking fuel. The adjusted association between 1 µg/m3 increase in PM₂.₅ was -27 ml (95%CI, -89 to 34) for FEV₁ and -5 ml (95%CI, -93 to 76) for FVC. The adjusted association between use of biomass was -112 ml (95% CI, -211 to -13) for FEV₁ and -142 ml (95%CI, -285 to 0) for FVC. The adjusted association was of greater magnitude for those with unvented stove (-158 ml, 95%CI, -279 to -36 for FEV₁ and -211 ml, 95%CI, -386 to -36 for FVC). CONCLUSIONS: We observed negative associations between ambient and household air pollution and lung function in young adults who had recently attained their maximum lung function. KEYWORDS: air pollution; lung function; India
Source: ISEE Conference Abstracts
Institutions: Universitat Pompeu Fabra, Barcelona Institute for Global Health, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Public Health Foundation of India, Indian Council of Medical Research, National Institute of Nutrition, Sri Ramachandra Institute of Higher Education and Research, University of Washington, London School of Hygiene & Tropical Medicine
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4316924785