Work

Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes

Year: 2023

Type: article

Abstract: Bacteria import vitamins and other essential compounds from their surroundings but also traffic related compounds from the cytosol to the cell envelope where they serve various functions. Studying the foodborne pathogen Listeria monocytogenes , we find that the modular use of subunits from a prominent class of bacterial transporters enables the import of environmental vitamin B 2 cofactors and the extracytosolic trafficking of a vitamin B 2 -derived cofactor that facilitates redox reactions in the cell envelope.

Source: mBio

DOI: 10.1128/mbio.03085-22

Authors: Rafael Rivera-Lugo, Shuo Huang, Frank Lee, Raphaël Méheust, Anthony T. Iavarone, Ashley M. Sidebottom, Eric Oldfield, Daniel A. Portnoy, Samuel H. Light

Institutions: University of California, Berkeley, University of Chicago, Centre National de la Recherche Scientifique, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, Génomique Métabolique du Genoscope, Genoscope, University of Illinois Urbana-Champaign

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,900

Funders: National Academies of Sciences, Engineering, and Medicine, Searle Scholars Program, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: High Definition Ion Mobility Spectrometer, G188459753, G210424055, G9000113756, G9000332176, How Listeria senses and responds to different host environments

OpenAlex ID: W4319295288

FWCI: 2.197

Cites: 59

Cited by: 16

Related to: 10