Year: 2022
Type: preprint
Abstract: Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To do so, we used retrospective data where patients have both a hemoglobin A1c and ECG measured. However, such patients may not be representative of the complete patient population. As part of the study, we proposed a methodology to evaluate our model in the target population by estimating the probability of receiving an A1c test and reweight the retrospective population to represent the general population. We also adapted an efficient algorithm to generate Shapley values for both ECG signals and demographic features at the same time for model interpretation. The model offers an automated, more accurate method for early diabetes detection compared to current screening efforts. Their potential use in wearable devices can facilitate large-scale, community-wide screening, improving healthcare outcomes.
Source: arXiv (Cornell University)
Institutions: New York University, NYU Langone Health, Tân Tạo University
Language: English
Topic: ECG Monitoring and Analysis
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Deep probabilistic predictive models for stroke and coronary heart disease, FW-HTF-RL: Collaborative Research: Future expert work in the age of "black box", data-intensive, and algorithmically augmented healthcare, G3329785188, Medical Scientist Research Service Award, G4353487559, NRT-HDR: FUTURE Foundations, Translation, and Responsibility for Data Science Impact, SCH: Multimodal representation learning and anomaly quantification for data-driven stroke rehabilitation, G6671297155, Career: Building Models that Avoid Spurious Correlations through Interpretability and Representation Learning, Medical Scientist Research Service Award, G8876996369, Clinical and Translational Science Award
OpenAlex ID: W4320855262
