Work

Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles

Year: 2023

Type: other

Abstract: Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles, i.e., exosome. The number of surface antigens of every extracellular vesicles can be quantified by both the high imaging resolution and stable brightness of upconversion nanoparticles. This method proves its great potential in nanoscale biological studies.

Source: Light Science & Applications

DOI: 10.1038/s41377-023-01106-5

Authors: Rui Pu, Qiuqiang Zhan

Institution: South China Normal University

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,095