Work

Memory retrieval, reconsolidation, and extinction: Exploring the boundary conditions of post-conditioning cue exposure

Year: 2023

Type: review

Abstract: Following fear conditioning, behavior can be reduced by giving many CS-alone presentations in a process known as extinction or by presenting a few CS-alone presentations and interfering with subsequent memory reconsolidation. While the two share procedural similarities, both the behavioral outcomes and the neurobiological underpinnings are distinct. Here we review the neural and behavioral mechanisms that produce these separate behavioral reductions, as well as some factors that determine whether or not a retrieval-dependent reconsolidation process or an extinction process will be in effect.

Source: Frontiers in Synaptic Neuroscience

DOI: 10.3389/fnsyn.2023.1146665

Authors: Nicole C. Ferrara, Janine L. Kwapis, Sydney Trask

Institutions: Rosalind Franklin University of Medicine and Science, Pennsylvania State University, Purdue University West Lafayette

Language: English

Topic: Memory and Neural Mechanisms

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,295

Funder: National Institute on Aging