Work

Graft rejection in component keratoplasty

Year: 2023

Type: article

Abstract: Among the various indications for keratoplasty, failed graft is one of the commonest indications in many published series. It is well known that the major cause of graft failure is endothelial rejection. In the last two decades, there has been a major paradigm shift in the surgical management of corneal diseases, and component keratoplasty has emerged from the concept of replacing the layer that is actually diseased, rather than replacing the full-thickness cornea with the traditional penetrating keratoplasty. This has resulted in improved outcomes and the risk of endothelial rejection has reduced drastically, thus expanding the survival time of the graft. In recent years, reports of graft rejection in component keratoplasty have emerged, with each having a different presentation and responding to a different line of treatment. This review aims to summarize the presentation, diagnosis, and management of graft rejections in component keratoplasty.

Source: Indian Journal of Ophthalmology

DOI: 10.4103/ijo.ijo_1964_22

Authors: Rashmi Deshmukh, Somasheila I Murthy, Christopher J Rapuano, Rasik B Vajpayee

Institutions: L V Prasad Eye Institute, Wills Eye Hospital, The University of Melbourne, The Royal Victorian Eye & Ear Hospital, Vision Eye Institute

Language: English

Topic: Corneal surgery and disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4323294261

FWCI: 1.625

Cites: 120

Cited by: 11

Related to: 10