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Successful living donor liver transplantation in a patient with hemophilia A and factor VIII inhibitor: A case report with perioperative recommendations

Year: 2023
Type: article
Study design: Case Report
Abstract: Liver transplantation in patients with end-stage liver disease and coexisting hemophilia A has been described. Controversy exists over perioperative management of patients with factor VIII inhibitor predisposing patients to hemorrhage. We describe the case of a 58-year-old man with a history of hemophilia A and factor VIII inhibitor, eradicated with rituximab prior to living donor liver transplantation without recurrence of inhibitor. We also provide perioperative management recommendations from our successful multidisciplinary approach.
DOI: 10.1016/j.ajt.2023.02.026
Authors: Reed W. Kamyszek, Suman L. Sood, Christopher J. Sonnenday, Neehar D. Parikh, Amanda Westman, Michael J. Englesbe, Seth A. Waits, Meredith Barrett, Robert J. Fontana, Sathish S. Kumar
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4323664664
FWCI: 0.532
Cites: 10
Cited by: 3
Related to: 10