Year: 2023
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: PURPOSE: To study the correlation between the vaginal microenvironment and human papillomavirus (HPV) infection by meta-analysis. METHODS: Databases including the Chinese Journal Full-text Database, China Science and Technology Journal, Wanfang, PubMed, Embase, Cochrane, and Web of Science were used to comprehensively retrieve published clinical studies on the correlation between the vaginal microenvironment and HPV infection. The retrieval was performed according to the inclusion and exclusion criteria, then qualified clinical studies were included for quality evaluation and data extraction. Revman 5.3 software was used for meta-analysis. The correlation between the vaginal microenvironment and HPV infection was assessed. The statistical results were shown by forest plots. Publication bias was tested by funnel plot. RESULTS: = 0.06). CONCLUSION: The vaginal microenvironment is closely related to HPV infection, especially aerobic vaginitis, bacterial vaginosis and trichomonal vaginitis are high-risk factors for HPV infection.
Source: PubMed Central
Authors: Jie Fu, Hong Zhang
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4324129150