Work

Fifty years on: Serotonin and depression

Year: 2023

Type: article

Abstract: It has been over 50 years since the original serotonin hypothesis was proposed by the British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the hypothesis. In this narrative review, we summarise the evidence for the serotonin hypothesis of depression, focusing on psychopharmacology and molecular imaging, as well as systems-level neuroscience.

Source: Journal of Psychopharmacology

DOI: 10.1177/02698811231161813

Authors: Sameer Jauhar, Philip J Cowen, Michael Browning

Institutions: King's College London, Warneford Hospital, University of Oxford

Language: English

Topic: Treatment of Major Depression

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,000