Year: 2023
Type: article
Abstract: Intestinal transplantation remains a challenging surgery that is performed in very select cases due to the organ’s specific characteristics: high sensibility to ischemia, increased risk of rejection, and longer length of hospital stay in comparison to other solid organ transplants. With deteriorating donor organ quality and safety, and increasing indications for intestinal transplantation, innovative and safe alternatives to increase the donor pool should be evaluated. In this review, we present a summary of organ machine perfusion history, trends, recent findings, challenges and the potential benefits and applications for intestinal transplantation. We performed a literature review of organ machine perfusion studies published in the last decade (2012-2022) for intestine, lungs, heart, liver, kidneys and pancreas and collected data from the United Network for Organ Sharing (UNOS) database aiming to show the trends of intestinal transplantation in the US and highlight the benefits of different perfusion techniques.
DOI: 10.57603/ejt-015
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4327946445