Work

Cell-Specific Expression of Human SIRT1 by Gene Therapy Reduces Retinal Ganglion Cell Loss Induced by Elevated Intraocular Pressure

Year: 2023

Type: article

Source: Neurotherapeutics

DOI: 10.1007/s13311-023-01364-6

Authors: Jipeng Yue, Reas S. Khan, Thu T. Duong, Kimberly E. Dine, Qi N. Cui, Nuala O'Neill, Puya Aravand, Tehui Liu, Brahim Chaqour, Kenneth S. Shindler, Ahmara G. Ross

Institution: University of Pennsylvania

Language: English

Topic: Glaucoma and retinal disorders

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Foundation Fighting Blindness, F. M. Kirby Foundation, Research to Prevent Blindness, Paul MacKall and Evanina Bell MacKall Trust, National Institutes of Health, National Eye Institute, Center for Advanced Retinal and Ocular Therapeutics, Perelman School of Medicine, University of Pennsylvania

Awards: Mitochondrial Respiratory Chain Dysfunction in Primary Open Angle Glaucoma, G338591007, The Development of Gene Therapy Using SIRT1 Signaling to Treat Chronic Glaucoma, Mechanism of SIRT1 Activator Mediated Neuroprotection of Retinal Ganglion Cells, PENN Vision Clinical Scientist Program

OpenAlex ID: W4328048126

FWCI: 3.854

Cites: 34

Cited by: 16

Related to: 10