Work

Associations of HPV-16 Gene Methylation With Oral HPV-16 Persistence Among a Multinational Sample of Men

Year: 2023

Type: article

Abstract: ABSTRACT: Using data from the Human Papillomavirus (HPV) Infection in Men cohort study, we demonstrate HPV-16 methylation associations with persistent oral HPV infection, the obligate precursor to oropharyngeal cancer. Human papillomavirus type 16 persistence was significantly associated with methylation of HPV-16 L2 CpG-4268 (Wilcoxon P = 0.04), and methylation of HPV-16 E2 CpG Pos 4 (Wilcoxon P = 0.04).

Source: Sexually Transmitted Diseases

DOI: 10.1097/olq.0000000000001802

Authors: Jessica Y. Islam, Deepti Bettampadi, Richard R. Reich, Belinda Nedjai, Anna R. Giuliano

Institutions: Moffitt Cancer Center, Queen Mary University of London

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of South Florida, National Cancer Institute