Work

Congenital lobar emphysema in monozygotic twins

Year: 2023

Type: article

Abstract: Congenital lobar emphysema (CLE) is caused by airway defects resulting in air trapping and hyperinflation of the affected lobe. Case reports of families affected with CLE imply a genetic etiology. However, the genetic contributions have not been well-described. We present a case of CLE in a monozygotic twin brother with respiratory distress diagnosed with right upper lobe (RUL) CLE and treated with a lobectomy. His asymptomatic twin brother was screened prophylactically, found to have RUL CLE and subsequently underwent a lobectomy. Our report provides further evidence supporting the genetic predisposition and potential benefit of early screening for CLE in comparable scenarios.

Source: Respiratory Medicine Case Reports

DOI: 10.1016/j.rmcr.2023.101842

Authors: Zeni Scott, Cynthia Zhou, Elisabeth Tracy, Mai K. ElMallah, Shatha Yousef

Institutions: Duke University, Duke Medical Center

Language: English

Topic: Congenital Diaphragmatic Hernia Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $930