Work

Editor's evaluation: Iron status influences mitochondrial disease progression in Complex I-deficient mice

Year: 2022

Type: peer-review

Abstract: In vivo studies reveal that mitochondrial Complex I deficiencies induce iron misregulation and liver iron overload that may contribute to neurodegeneration in mitochondrial disease mice, and that iron restriction is effective in reducing disease progression.

DOI: 10.7554/elife.75825.sa0

Author: Yvette Yien

Institution: University of Pittsburgh

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4360597487

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