Work

Development and Validation of TaqMan Chemistry Probe-Based Rapid Assay for the Detection of Echinocandin-Resistance in Candida auris

Year: 2023

Type: article

Abstract: Candida auris is a multidrug-resistant yeast pathogen causing outbreaks in health care facilities worldwide, and the emergence of echinocandin-resistant C. auris is a concern. Currently used Clinical and Laboratory Standards Institute (CLSI) and commercial antifungal susceptibility tests (AFST) are phenotype-based, slow, and not scalable, limiting their effectiveness in the surveillance of echinocandin-resistant C. auris .

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.01767-22

Authors: YanChun Zhu, Kelli M. Hager, Swati R. Manjari, Nilesh K. Banavali, Vishnu Chaturvedi, Sudha Chaturvedi