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Supplementary Figures S1-S7 from Genetic Hitchhiking and Population Bottlenecks Contribute to Prostate Cancer Disparities in Men of African Descent

Year: 2023

Type: supplementary-materials

Abstract: Figure S1. Bioinformatics pipeline. Figure S2. Empirical vs. simulated genetic risk scores for each population. Figure S3. Many SNPs contribute to differences in risk on both a continental and subcontinental scale. Figure S4. Unweighted vs. weighted genetic risk scores for each population. Figure S5. Scans of selection in the 2q37 region. Figure S6. Scans of selection in the 22q13 region. Figure S7. Scans of selection in the 8q24 region.

DOI: 10.1158/0008-5472.22417874.v1

Authors: Joseph Lachance, Ali J. Berens, Matthew E.B. Hansen, Andrew K. Teng, Sarah A. Tishkoff, Timothy R. Rebbeck

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361235262

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